If another person has overdosed and it has critical signs or symptoms like passing out or issues respiration, phone 911. Usually, contact a poison control Middle without delay.
Warning must be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to your nursing woman.
The risk for severe respiration troubles is larger when you start this medication, or if you are taking the wrong dose or get extra of this medication than prescribed. Getting this medication with Liquor or other prescription drugs that could cause drowsiness or respiratory issues may possibly cause really serious Unwanted side effects, such as death. Also, other drugs can have an effect on the removing of the product from your entire body, which may have an affect on how it really works.
Drug interactions might adjust how your medications operate or increase your hazard for severe side effects. This doc isn't going to comprise all possible drug interactions.
This medication can make you far more delicate towards the Solar. Keep out on the sun. If You can't stay away from getting within the sun, don protecting clothing and use sunscreen. Don't use Sunshine lamps or tanning beds/booths.
Codeine has superior antitussive activity, Despite the fact that under that of morphine at equal doses. It can be used in preference to morphine, due to the fact Unwanted side effects are infrequent at the standard antitussive dose of codeine.
This medication may perhaps contain sugar and/or Promethazine codeine syrup Liquor. Warning is encouraged When you have diabetic issues, Liquor dependence, or liver disorder. Inquire your medical professional or pharmacist about working with this product safely and securely.
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Bone-Marrow Despair – Promethazine really should be made use of with warning in sufferers with bone-marrow depression. Leukopenia and agranulocytosis are actually reported, generally when promethazine HCl has actually been Employed in Affiliation with other known marrow-harmful agents.
Respiratory depression bringing about arrest, coma, and Loss of life has happened with using codeine antitussives in young little ones, especially from the underneath-one particular-yr infants whose capability to deactivate the drug will not be thoroughly developed.
Warning people that some people have a variation in a liver enzyme and alter codeine into morphine a lot more promptly and wholly than Others. These folks are extremely-rapid metabolizers and usually tend to have larger-than-standard levels of morphine inside their blood right after having codeine, which may result in overdose indicators for instance Excessive sleepiness, confusion, or shallow respiratory. In most cases, it's not known if another person is an ultra-rapid codeine metabolizer.
Antihistamines and codeine are the two contraindicated for use in the treatment method of decreased respiratory tract indications, such as bronchial asthma.
Even so, aged people usually tend to have age-relevant liver, kidney, or coronary heart problems, which can call for caution and an adjustment within the dose for clients acquiring codeine, phenylephrine, and promethazine mixture. Breastfeeding Studies in Ladies breastfeeding have demonstrated dangerous toddler outcomes. An alternative to this medication needs to be prescribed or you'll want to cease breastfeeding even though applying this medication.
Since narcotic analgesics might increase biliary tract strain with resultant improves in plasma amylase or lipase amounts, willpower of these enzyme stages may be unreliable for 24 hrs after a narcotic analgesic has been presented.